The Reds take on the Seagulls on top form, having beaten West Ham 4-0 and Crystal Palace 2-0 in their opening two fixtures.
But Chris Hughton’s led visitors are in good spirits themselves, having bounced back from a 2-0 loss at Watford by beating Manchester United 3-2.
This will be the 28th meeting between
the two sides in competitive action,
with the home side winning the
majority of the games (15), and just
four wins for the visitors.
Jurgen Klopp has very little to worry about.
Alex Oxlade-Chamberlain is out for the whole season with a knee injury, but Dejan Lovren (pelvis) is the only other absentee.
Joel Matip, is fit again and will challenge Joe Gomez for his centre-back spot alongside Virgil van Dijk in Lovren’s absence.
Trent Alexander-Arnold and Andrew Robertson have the full-back spots nailed down. Fabinho, Jordan Henderson and Adam Lallana are all in contention.
Hughton has to make at least one change to the team that beat United, as Lewis Dunk is out injured for several weeks with an ankle problem he picked up against Manchester United.
Gaetan Bong should keep his place at left-back ahead of Bernardo, while right-back Martin Montoya will almost definitely start as Bruno is out with a hamstring injury.
Striker Florin Andone has a groin issue, while winger Jose Izquierdo is still out with a knee injury.
New signings Alireza Jahanbakhsh and Yves Bissouma will be hoping for a chance to shine soon, but last week Hughton preferred Jurgen Locadia and Beram Kayal off the bench.
Tomer Hemed has left the Amex Stadium for a loan spell at QPR, so is no longer an option.
The match kicks off at 5.30pm on Saturday,
Liverpool (4-3-3): Alisson; Alexander-Arnold, Gomez, Van Dijk, Robertson; Milner, Wijnaldum, Keita; Salah, Mane, Firmino
Brighton (4-4-1-1): Ryan; Montoya, Duffy, Balogun, Bong; Knockaert, Stephens, Propper, March; Gross; Murray.